Endocrine Abstracts

Vitamin D binding protein (VDBP) has a critical role in orchestrating optimal vitamin D homeostasis and bioavailability. VDBP has been implicated in modulating the gene expression of amino-transporters within the placenta and might thus control the transfer of amino acids to neonates during in utero development. We hypothesize that dyshomeostasis of VDBP could lead to adverse metabolic profiles and low birth weight in neonates. VDBP genetic polymorphisms steer the uni...